发布于:2019-10-31
鲍宝龙,男,生于1970年6月,浙江临海人,博士,生物系鱼类学教研室教授、博士生导师。曾获得上海市“东方学者”, 浦江学者,江苏省双创人才等称号。1991年毕业于浙江水产学院海水养殖专业本科,1996年获上海水产大学水产养殖农硕士学位,2006年获复旦大学遗传学博士学位。2004 年3月至2005年8月,美国Auburn大学访问学者,2007年9月至2009年9月,美国Nebraska- Lincoln大学博士后。兼任中国鱼类学会理事、中国水产学会水产生物技术专业委员会理事、中国渔业协会河豚鱼分会理事。
教学工作情况
承担鱼类学、鱼类学实验等本科课程
承担分子发育生物学、比较基因组学等硕士研究生课程
主要研究方向
[1]鱼类变态发育生物学的研究,主要集中在比目鱼类变态的研究
[2]鱼类和细菌协同进化的研究,主要集中在河�和河�毒素细菌的研究
主持和参与的科教项目
[1]国家自然科学基金面上项目:比目鱼类体色左右不对称及体色异常产生的机理, 主持
[2]国家自然科学基金面上项目:TTX合成相关基因在河�体内各种产TTX共生细菌间的水平转移规律。主持
[3]国家自然科学基金面上项目:细胞分裂和细胞迁移对比目鱼类眼睛移动的作用,主持
[4]国家自然科学基金面上项目:甲状腺激素调控比目鱼眼睛移动的细胞分裂信号途径,主持
[5]上海市浦江计划:河�毒素合成相关基因的鉴定及人工进化,主持
发表的主要论文情况
[1]Sun M, Wei F, Li H, Xu J, Chen X, Gong X, Tian Y, Chen S, Bao B, 2015, Distortion of frontal bones results from cell apoptosis by the mechanical force from the up-migrating eye during metamorphosis in Paralichthys olivaceus. Mechanism of Development,136, 87-98.(通讯作者)
[2]Liu J, Wei F, Lu Y, Ma T, Zhao J, Gong X, Bao B,2015,Production level of tetrodotoxin in Aeromonas is associated with the copy number of a plasmid. Toxicon,101:27-34. (通讯作者)
[3]Wei F, Ma T, Gong X, Zhang N, Bao B, 2015, Identification of tetrodotoxin-producing bacteria from goby Yongeichthys criniger. Toxicon, 104:46-51. (通讯作者)
[4]Yao W, Lv Y, Gong X, Wu J, Bao B, 2015, Different ossification patterns of intermuscular bones in fishes with different swimming modes. Biology Open, 4(12):1727-1732. (通讯作者)
[5]Li L, Zheng J, Bao B, Berendzen PB, 2013,Change of eye shape during the metamorphosis in two flatfishes Paralichthys olivaceus and Solea senegalensis, with comparison of eye shape within the Pleuronectiformes. Ichthyological Research, 60(2):178-183. (通讯作者)
[6]Bao B,Rodriguez-Melendez R, Zempleni J, 2012, Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. Journal of Nutritional Biochemistry, 23 : 635�639.
[7]Bao B,Wijeratne SK,Rodriguez-Melendez R, Zempleni J, 2011, Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity. Biochemical and Biophysical Research Communications, 412 (1): 115-120.
[8]Jiang Y, Yang G, Xie C, Gong X, Bao B, 2011, Cellulase-producing bacteria Aeromonas veronii and Aeromonas hydrophila are dominant populations as indigenous species in intestinal of grass carp Ctenopharyngodon idellus (Valenciennes). Aquaculture Research, 42(4): 499-505. (通讯作者)
[9]Bao B, Ke Z, Xing J, Peatman E, Liu Z, Xie C, Xu B, Gai J, Gong X, Yang G, Jiang Y, Tang W, Ren D, 2011, Proliferating cells in suborbital tissue drive eye migration in flatfish. Developmental Biology, 351:200-207.
[10]Bao B, Pestinger V, Hassan Y, Borgstahl GEO, Kolar C, Zempleni J, 2011, Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. Journal of Nutritional Biochemistry, 22: 470-475.
[11]Xie C, Xu S, Yang L, Ke Z, Jiang Y, Xing J, Gong X, Xu L, Bao B, 2011, mRNA/microRNA profile at metamorphic stage of Oliver Flounder, Paralichthys olivaceus. Comparative and Functional Genomics,2011:1-12. (通讯作者)
[12]Yang G, Xu J, liang S, Ren D, Yan X, Bao B, 2010, A novel TTX-producing bacteria of Aeromonas isolated from the ovary of Takifugu obscurus. Toxicon, 56:324-329. (通讯作者)
[13]Bao B, Rodriguez-Melendez R, Wijeratne SSK, Zempleni J, 2010, Biotin Regulates the Expression of Holocarboxylase Synthetase in the miR-539 Pathway in HEK-293 Cells. Journal of Nutrition, 140(9):1546-1551.
[14]Yang G, Bao B, Peatman E, LiH.,HuangL.,RenD, 2007. Analysis of the composition of the bacterial community in puffer fish Takifugu obscurus. Aquaculture, 262:183-191. (通讯作者)
[15]Xu B, Wang S, Jiang Y, Yang L, Li P, Xie C, Xing J, Ke Z, Li J, Gai J, Yang G, Bao B, Liu Z. 2010,Generation and analysis of ESTs from the grass carp, Ctenopharyngodon idellus. Animal Biotech, 21(4): 217-225. (通讯作者)
[16]Bao B, Peatman E, Xu P, Li P, Zeng H, He C, Liu Z, 2006.The catfish liver-expressed antimicrobial peptide 2 (LEAP-2) gene is expressed in a wide range of tissues and developmentally regulated. Molecular Immunology 43(4):367-377.
[17]Peatman E, Bao B, Xu P, Baoprasertkul P, Liu Z,2006,Catfish CC chemokines: genomic clustering, duplications, and expression after bacterial infection with Edwardsiella ictaluri. Molecular Genetics and Genomics 275(3):297-309(共同第一作者)
[18]Bao B, Peatman E, Peng X, Baoprasertkul P, Wang G, Liu Z,2006, Characterization of 23 CC chemokine genes and analysis of their expression in channel catfish (Ictalurus punctatus). Dev Comp Immunol, 30(9):783-796.
[19]Bao B, Peatman E, Li P, He C, Liu Z, 2005. Catfish hepcidin gene is expressed in a wide range of tissues and exhibits tissue-specific upregulation after bacterial infection. Development and Comparative Immunology, 29: 939-950.
[20]Bao B, Yang G, Liu Z, Li S, Wang Z, Ren D, 2005, Isolation of SFRS3 gene and its differential expression during metamorphosis involving eye migration of Japanese flounder Paralichthys olivaceus. Biochimica et Biophysica Acta General Subjects, 1725(1):64-70.
申请和授权专利情况
[1]鲍宝龙、柯中和、邢巨斌、龚小玲、谢彩霞、徐冰、盖军伟.所有申请人姓名. 一种抑制比目鱼眼睛移动的方法.专利号:ZL201010179362.3(发明专利)
[2]鲍宝龙、杨桂梅. 产河豚毒素的气单胞菌发酵培养和所产河豚毒素的检测方法.专利号:ZL201010179363.8(发明专利)
[3]鲍宝龙、卢瑛、马廷龙、李静、刘静、张莉君.降解河豚毒素的提取液及其制备方法.专利号:ZL201310135898.9(发明专利)
[4]鲍宝龙、姚文杰、吕耀平、张莉君.一种抑制鱼鳞形成的方法. 专利号:ZL201310329623.9(发明专利)
专著和教材情况
[1]主编译著《水产基因组学技术》,中国化工出版社,2011年4月第1版
科教工作获奖情况
[1]2004年,《鱼类学》CAI课件,高等教育上海市级教学成果三等奖
[2]2004年,中国五大湖三角帆蚌优异种质评价与筛选,上海市科学技术进步三等奖
[3]2009年,鱼类学精品课程建设的探索与实践,上海市教学成果奖一等奖
[4]2010年,“CC趋化因子在斑点叉尾�抗菌感染中免疫响应模式的研究”,上海海洋大学科技成果三等奖
[5]2012年,“校优秀教育工作者”称号获得者
联系方式
地址:水产与生命学院B203
电话:021-61900426
E-mail:blbao@shou.edu.cn