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吴文惠

发布于：2019-10-31

吴文惠

　　吴文惠，男，满族，博士，上海海洋大学教授，博士生导师。1965年出生，内蒙古人。1986年毕业于内蒙古农业大学生物工程专业，获学士学位，1989年毕业于山东农业大学植物生理生化专业，获硕士学位， 2004年毕业于东京农工大学生物工程专业，获博士学位。现任中国生物化学与分子生物学学会海洋生物化学与分子生物学分会副理事长，上海药学会海洋药物专业委员会副主任委员。浦江学者。主要研究方向是海洋药物化学、心血管药理学和海洋功能性食品。主持国家自然科学基金项目、国家863项目子课题、上海市创新行动计划等20 余项科研课题。在国内外主要学术刊物上发表论文百余篇，出版海洋药物导论等专著4册，授权国家发明专利7项。指导多名研究生获得硕士和博士学位。多次参加国际国内学术交流活动。被授予上海海洋大学优秀教育工作者、上海海洋大学科技成果奖、农业部科技进步二等奖等荣誉。
　　

近期发表的主要论文：

  1. ChaoYan Zhang, Ting Kong,Wen Hui Wu and Min Bo Lan. The Protection of Polysaccharide from the Brown Seaweed Sargassum graminifolium against Ethylene Glycol-Induced Mitochondrial Damage. Marine Drugs, 2013; 11: 870-880.

     

  2. Xiaolin Xu, Qing Zhu, Hui Lv, Wenhui Wu, Min Lv, Kehai Liu. Isolation and biological activities of citral from sweet orange oil. Advanced Materials Research, 2013; 750-752: 1621-1625.

     

  3. Ting Kong, Chaoyan Zhang, Bin Bao, Long Sha, Zhen Wang and Wenhui Wu. Optimized formulation of APN toothpaste with biochemical materials using response surface methodology. Advanced Materials Research, 2013; 676: 108-113.

     

  4. Yong Xian Wang, Wen Hui Wu, Bao Bin, Rui Rui Song, Li Chun Sun. Effect of Fibrinolytic Compound GDG on Crystal Structure of Lysozyme. Advanced Materials Research, 2012; 554-556: 1768-1775.

     

  5. Lijuan chen , Bin Bao , Nanping Wang , Jing Xie and Wenhui Wu. Oral Administraion of Shark Type Ⅱ Collagen Suppresses Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats. Pharmaceuticals, 2012; 5:339-352.

     

  6. Kang Jun-Xia,Kang Yong-Feng, Wen-Hui Wu. Effects of Metal Ions and pH on Thermal Stability of Whale Sharp (Rhincodon typus) Skin Collagen[J], Food Science, 2011; 32(13): 66-70.

     

  7. Song Rui-rui, Bao Bin, Bu Yong-shi, Wang Yong-xian，Chen Li-juan，Wu Wen-hui. Physico-chemical Characteristics of Type Ⅱ Collagen Isolated from Prionace glauca Cartilage[J], Food Science, 2013; 34(9): 24-27.

     

  8. Elango Jeevithan , Bin Bao , Jingyi Zhang , Shaotong Hong , Wenhui Wu. Purification, characterization and antioxidant properties of low molecular weight collagenous polypeptide (37 kDa) prepared from whale shark cartilage (Rhincodon typus). J Food Sci Technol, 2015, 52(10): 6312-6322.

     

  9. Elango Jeevithana, JingyiZhang, Nanping Wang, Lan He, Bin Bao, Wenhui Wu.  Physico-chemical, antioxidant and intestinal absorption properties ofwhale shark type-II collagen based on its solubility with acid andpepsin. Process Biochemistry, 2015, 50: 463-472.

     

  10. Ting Yan, Wenhui Wu, Tongwei Su Jiajie Chen, Quangang Zhu, Chaoyan Zhang, Xiaoyu Wang, Bin Bao. Effects of a novel marine natural product: pyrano indolone alkaloid fibrinolytic compound on thrombolysis and hemorrhagic activities in vitro and in vivo. Arch. Pharm. Res. 2015, 38:1530-1540.

     

  11. Shanqiao Chen, Chunhua Zhang, Yuefeng Xiong, Xiaoqing Tian, Chengchu Liu, Elango Jeevithan, Wenhui Wu. A GC-MS-based metabolomics investigation on scallop (Chlamys farreri) during semi-anhydrous living-preservation. Innovative Food Science and Emerging Technologies, 2015, 31: 185-195.

     

  12. ZhouYu,Wenhui Wu, Zhao Qing-Bo, Wang Xiao-Yu, Bao Bin. Inhibition of HMG-CoA reductase by MFS, a purified extract from the fermentation of marine fungus Fusarium solani FG319, and optimization of MFS production using response surface methodology. Chinese Journal of Natural Medicines 2015, 13(5): 0346-0354.

     

  13. Elango Jeevithan, Bao Bin, Chen Shan qiao,  Yu Y, Jeyashakila R, WenHui Wu. Type-II collagen derived from marine environs: An extended review for its mechanism of action in oral tolerance and its biomarkers for the detection of arthritis disease in earlier stage. World Journal of Pharmacy and Pharmaceutical Sciences, 2015,4,10,215-23.

     

  14. Elango Jeevithan, Bin B, Yongshi B, Yu Zhou, Qingbo Zhao,Wenhui Wu. Type II Collagen and Gelatin from Silvertip Shark (Carcharhinus albimarginatus) Cartilage: Isolation, Purification, Physicochemical and Antioxidant Properties. Marine Drugs, 2014, 12(7), 3852-3873.  

     

  15. Elango Jeevithan, Wenhui Wu, Wang N, He L, Bin Bao. Isolation, purification and characterization of pepsin soluble collagen isolated from silvertip shark (Carcharhinus albimarginatus) skeletal and head bone. Process Biochemistry, 2014, 49(10), 1767�1777 .

     

  16. Li Wei, Chen Shanqiao, Wang Xu, Li huiting, Shujun Wang, Xiaofeng He, Bin Bao, Wenhui Wu. The recovery effects of Perinereis aibuhitensis Grube added to enteral immune-enhancing nutrition in severely burned mice[J]. Rsc Advances, 2016, 6(95):92705-92715.  

     

  17. Jeevithan Elango, Jingyi Zhang, Bin Bao, Krishnamoorthy Palaniyandi, Shujun Wang, Wu Wenhui,Jeya Shakila Robinson. Rheological, biocompatibility and osteogenesis assessment of fish collagen scaffold for bone tissue engineering.[J]. International Journal of Biological Macromolecules, 2016, 91:51-59.  

     

  18. Ge Wang, Wenhui Wu, Quangang Zhu, Shiqing Fu, Xiaoyu Wang, Shaotong Hong, Ruihua Guo and Bin Bao. Identification and Fibrinolytic Evaluation of an Isoindolone Derivative Isolated from a Rare Marine Fungus Stachybotrys longispora FG216. Chinese journal of chemistry, 2015, 33(9): 1089-1095. 

     

  19. Elango Jeevithan, Jingyi Zhang, Bao Bin, Shujun, Wang, JeyaShakila, Wenhui Wu, .   Biocompatibility assessment of type-II collagen and its polypeptide for tissue engineering: effect of collagen's molecular weight and glycoprotein content on tumor necrosis factor (Fas/Apo-1) receptor activation in human acute T-lymphocyte leukemia cell line.14:236-14246.

     

  20. Elango Jeevithan,, Robinson J S, Geevaretnam J, wenhui Wu. Physicochemical and Rheological Properties of Composite Shark Catfish ( P angasius pangasius ) Skin Collagen Films Integrated with Chitosan and Calcium Salts[J]. Journal of Food Biochemistry,  40 (2016) 304�315.

     

  21. Mingsheng Lu, Zhi Shan, Kori Andrea, Bruce MacDonald, Stefanie Beale, Dennis E. Curry, Li Wang, Shujun Wang, Ken D. Oakes, Craig Bennett, Wenhui Wu, and Xu Zhang. Chemisorption Mechanism of DNA on Mg/Fe Layered Double Hydroxide Nanoparticles: Insights into Engineering Effective SiRNA Delivery Systems.[J]. Langmuir the Acs Journal of Surfaces & Colloids, Langmuir, 2016, 32 (11): 2659�2667.

     

  22. Jingyi Zhang, Elango Jeevithan, Bin Bao, Shujun Wang, Kaili Gao, Chaoyan Zhang, Wenhui Wu. Structural characterization, in-vivo acute systemic toxicityassessment and in-vitro intestinal absorption properties of tilapia (Oreochromis niloticus) skin acid and pepsin solublilized type I collagen. Process Biochemistry,  2016, 51:2017�2025. 

     

  23. 吴文惠，张艳，包斌，李燕.不同鲨鱼皮胶原蛋白的分离及其特性研究.中国海洋药物杂志，2008,27(2):22-28.

  24. 吴文惠，朱夕波，包斌，杨怀玉，周培根，杨兴群，曹张军，缪辉南.水鲨头皮胶原蛋白分离及其部分特性研究.中华航海医学与高气压医学杂志，2007,14(4):230-232.

  25. 吴文惠，殊亚，包斌，陆魏，何培根，张艳，张兴群，缪辉南，曹张军.温和条件下分离马鲛鲨皮胶原蛋白的方法及其部分特性研究.中华航海医学与高压气压医学杂志，2007,14(3):133-136.

  26. 陈丽娟，吴文惠，王南平，谢晶，包斌.鲤鱼鱼鳞硬蛋白的营养学评价.水生动物营养，2011,63(04):63-66.

  27. 宋瑞瑞，包斌，卜永士，王永先，陈丽娟，吴文惠.Ⅱ型胶原蛋白的热稳定性、圆二色性和红外光谱研究。中国海洋药物，2013,32(1):55-62.

  28. 康俊霞，康永锋，包斌，陈志伟，谢晶，吴文惠.Na+、Ca2+和pH值对鲸鲨皮胶原蛋白热变性温度的影响.食品科学，2011,32(13):66-70.


    　　联系方式
    　　地 址：上海市临港新城沪城环路999号，上海海洋大学
    　　电 话：021-61900388，15692165917
    　　e-mail:     whwu@shou.edu.cn
    　　邮政编码：201306

 

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