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牛东红

发布于:2021-07-20


牛东红,女,19788月生,河北人,博士,教授,博士生导师,水产种质与育种系教师。2001年毕业于河北大学生物学专业,理学学士;2004年毕业于河北大学水生生物学专业,理学硕士;2009年毕业于上海海洋大学水产养殖学专业,农学博士。于2010-2011年和2017-2018年在美国Auburn University农学院水产系遗传学实验室进行留学访问。要从事海洋贝类遗传育种与基因组学方向的科研工作承担国家重点研发计划项目和国家自然科学基金项目,担任国家自然科学基金一审评审专家,为上海市高水平地方高校创新团队和江苏省高校协同创新中心骨干,中国水产学会、动物学会和贝类学分会会员,已发表科研论文七十余篇,并培育获得水产新品种缢蛏申浙1

教学工作情况

本科生课程《遗传学》、《遗传学实验》、《神奇的海洋贝类》

研究生课程《论文写作与学术规范》、《贝类生物学及养殖》、《水产动物遗传育种》

 主要研究方向

主要从事海洋贝类遗传育种与基因组学方向的科研工作

 主持和参与的科教项目

[1]     2019.11-2022.12国家重点研发计划海水池塘和盐碱水域生态工程化养殖技术与模式项目子任务(主持)

[2]     2019.11-2022.12国家重点研发计划滩涂增养殖技术与生态农牧化新模式项目(参与)

[3]     2019.12-2021.12 江苏省海洋生物技术重点实验室开放课题缢蛏儿茶酚胺受体在幼虫发育过程中的作用(主持)

[4]     2018.01-2020.12 水产双一流学科建设项目水产种质资源研究与支撑平台能力提升(参与)

[5]     2017.01-2017.12 校级教学改革和教学管理面上项目以培养创新型人才为目标的遗传学教学改革(主持)

[6]     2016.09-2018.06 校级教学团队建设项目遗传育种教学实践与科创能力创新教学团队(参与)

[7]     2015.01-2018.12 国家自然科学基金面上项目 “缢蛏幼虫变态过程IGFBPs基因调控的分子基础研究(主持)

[8]     2013.01-2017.12水产动物遗传育种中心上海市协同创新中心项目缢蛏遗传育种服务团队(参与)

[9]     2012.01-2014.12 国家自然科学青年基金 “缢蛏生长相关基因SNPsCNPs与生长性状的关联分析(主持)

[10]2012.01-2015.12 国家“863”计划项目主要养殖双壳贝类良种培育子课题 “缢蛏良种培育(参与)

 发表的主要论文(第一或通讯作者)

[1]     Zhi Li, Donghong Niu, Maoxiao Peng, Ya Xiong, Jie Ji, Zhiguo Dong, Jiale Li. Dopamine beta-hydroxylase and its role in regulating the growth and larval metamorphosis in Sinonovacula constricta. Gene. DOI:10.1016/ j.gene. 2020.144418

[2]     Donghong Niu, Zhi Li, Yunchao Du, Shengyao He, Zhiguo Dong, Jiale Li*. Identification of a dopamine receptor in Sinonovacula constricta and its antioxidant responses. Developmental & Comparative Immunology. 2020(103): 1-7.

[3]     卫侃韵,谢淑媚,王沈同,陈宇宽, 牛东红*,李家乐.缢蛏EGFR基因内含子1SNP位点多态性与生长性状相关性[J].水产学报,2019,43(02):483-491

[4]     何圣耀,杜蕴超,牛东红*,李家乐. 缢蛏β2肾上腺素能受体基因及其在损伤修复中的作用. 基因组学与应用生物学, 2019, 1-10.

[5]     杜蕴超, 何圣耀, 谢淑媚, 牛东红*, 李家乐. 多巴胺受体拮抗剂对缢蛏多巴胺D2类受体的影响[J]. 基因组学与应用生物学, 2019, 38(06):2476-2482.

[6]      Yan Li, Donghong Niu*, Yuqi Bai, Tianyi Lan, Maoxiao Peng, Zhiguo Dong,  Jiale Li*. Characterization of the ScghC1q-1 gene in Sinonovacula constricta and its role in innate immune responses. Developmental & Comparative Immunology, 2019, 94:16-21

[7]      Yan Li, Donghong Niu*, Yuqi Bai, Tianyi Lan, Maoxiao Peng, Zhiguo Dong,  Jiale Li*. Identification of a novel C1q complement component in razor  clam Sinonovacula constricta and its role in antibacterial activity. Fish & Shellfish Immunology, 2019, 87: 193-201.

[8]      Yuqi Bai, Donghong Niu*, Yan Li, Yulin Bai, Tianyi Lan, Maoxiao Peng,  Zhiguo Dong, Fanyue Sun, Jiale Li*. Identification and characterisation  of a novel small galectin in razor clam (Sinonovacula constricta) with multiple innate immune functions. Developmental & Comparative Immunology, 2019, 93:11-17.

[9]      Yuqi Bai, Donghong Niu*, Yulin Bai, Yan Li, Tianyi Lan, Maoxiao Peng,  Zhiguo Dong, Jiale Li*. Identification of a novel galectin in Sinonovacula constricta, and its role in recognition of gram-negative bacteria. Fish & Shellfish Immunology. 2018,80:1-9

[10]杜蕴超,谢淑媚,何圣耀,牛东红*, 李家乐. 缢蛏多巴胺受体基因及其在损伤修复中的作用[J].热带海洋学报,2018,37(03):45-54.

[11]Kanyun  Wei, Donghong Niu*, Maoxiao Peng, Shumei Xie, Shentong Wang, Jiale Li.  Characterization of two splice variants of EGFR and their effects on the  growth of the razor clam [J]. Aquaculture and Fisheries, 2018,3(2):  62-31

[12]Donghong Niu, Ya Xiong, Maoxiao Peng, Xue Meng,Tianyi Lan, Jiale Li*. Hemolytic reactions in the hemolymph of bivalve Sinonovacula constricta sh ow complement-like activity. Fish & Shellfish Immunology, 2018, 79, 11-17.

[13]牛东红, 汪桂玲, 李家乐. 以培养科研素养为目标的遗传学教学模式探索,高校生物学教学研究(电子版)(核心遴选库), 2018, 8(1): 13-16

[14]牛东红, 陈丽平, 汪桂玲. 遗传学实验中注重提高实践能力----以人类性别决定基因扩增为例,教育教学论坛, 2018, 51: 51-52

[15]Shumei  Xie, Donghong Niu*, Yunchao Du, Kanyun Wei, Hai Dang Nguyen, Jiale Li.  Expression and characterization of insulin-like growth factor II mRNA  binding protein in the razor clam Sinonovacula constricta, Aquaculture and Fisheries, 2017, 2(6):247-255.

[16]Donghong  Niu, Yunchao Du, Ze Wang, Shumei Xie, Hai-Dang Nguyen, Zhiguo Dong,  Heding Shen, Jiale Li*. Construction of the first high-density genetic  linkage map and analysis of quantitative trait loci for growth-related  traits in Sinonovacula constricta[J]. Marine Biotechnology, 2017,19 (5):488–496. 

[17]牛东红, 沈玉帮, 汪桂玲, 白志毅. 亲子鉴定技术在遗传学实验教学中的应用. 教育教学论坛, 2017, 46: 247-249

[18]Donghong Niu, Fei Wang, Shumei Xie, Fanyue Sun, Ze Wang, Maoxiao Peng, Jiale Li*. Developmental transcriptome analysis and identification of genes involved in larval metamorphosis of the razor clam, Sinonovacula constricta. Marine Biotechnology, 2016, 18(2):168-175.

[19]Donghong Niu1, Fei Wang1, Honggang Zhao, Ze Wang, Shumei Xie, Jiale Li*. Identification, expression, and innate immune responses of two insulin-like peptide genes in the razor clam Sinonovacula constricta. Fish & Shellfish Immunology.2016, 51:401-404

[20]Thi-Nga Tran 1, Dong-Hong Niu 1, Hai-Dang Nguyen, Shu-Mei Xie, Jia-Le Li*. Populations genetic structure of the razor clam Sinonovacula constricta from china, korea and vietnam.Biochemical Systematics and Ecology, 2015, 61: 429-436

[21]谢淑媚, 牛东红*, 阮海灯, 王泽, 王飞, 陈世娥, 李家乐. 缢蛏IGFBP基因结构及生长性状相关的SNP筛选., 水产学报,2015, 39(6): 799-809.

[22]Donghong  Niu, Lie Wang, Zhiyi Bai, Shumei Xie, Honggang Zhao, Jiale Li.   Identification and expression characterization of the myostatin (MSTN)  gene and association analysis with growth traits in the razor clam  Sinonovacula constricta. Gene, 2015, 555(2):297-304

[23]Donghong Niu, Shumei  Xie, Zhiyi Bai, Lie Wang, Kai Jin, Jiale Li *.  Identification,  expression, and responses to bacterial challenge of the cathepsin C gene  from the razor clam Sinonovacula constricta.Developmental and Comparative Immunology, 2014, 46(2): 241-245.

[24]Donghong Niu, Lie Wang, Fanyue Sun, Zhanjiang Liu, Jiale Li*. Development of molecular resources for an intertidal clam, Sinonovacula constricta using 454 transcriptome sequencing. PLoS ONE, 2013, 8(7): e674562013.

[25]Donghong Niu, Kai  Jin, Lie Wang, Bingbing Feng, Jiale Li*. Molecular characterization and  expression analysis of novel cathepsin L genes in the razor clam, Sinonovacula constricta. Fish and Shellfish Immunology, 2013, 35(2): 581-588.

[26]Donghong  Niu, Kai Jin, Lie Wang, Fanyue Sun, Jiale Li*. Molecular  characterization and expression analysis of cathepsin B gene in the  razor clam, Sinonovacula constricta. Developmental & Comparative  Immunology, 2013, 41(1): 94-99 

[27]Lie Wang 1, Donghong Niu 1, Jiale Li *. Charaterization of novel EST-derived SNP markers by using 454 pyrosequencing in Sinonovacula constricta. Conservation Genetics Resources. 2013,5(1): 191-193.

[28]Donghong Niu,  Bingbing Feng, Dabo Liu , Yumin Zhong, Heding Shen, Jiale Li*.  Significant genetic differentiation of 10 populations of the razor clam (Sinonovacula constricta) along the coast of China revealed by microsatellite analysis. Zoological Studies. 2012,51(3): 406-414

[29]Donghong Niu, Eric  Peatman, Hong Liu, Jianguo Lu, Huseyin Kucuktas, Shikai Liu,Fanyue Sun,  Hao Zhang, Tingting Feng, Zunchun Zhou, Jeffery Terhune, Geoff  Waldbieser, Jiale Li, Zhanjiang Liu*. Microfibrillar associated protein 4 (MFAP4) genes in catfish play a nove lrole in innate immune responses. Developmental & Comparative Immunology, 2011, 35(5): 568-579.

授权专利

[1]     牛东红,杜蕴超,李家乐,彭茂潇,卫侃韵,谢淑媚,蓝天一。一种高效的双壳贝类血淋巴的提取方法。发明专利。专利号: ZL201610006424.8

[2]     李家乐,彭茂潇,牛东红,谢淑媚,黄文吉,王飞,王泽,卫侃韵,杜蕴超.一种防毒凝胶切割器的割胶方法。发明专利。专利号ZL201510300790.X

[3]     李家乐,白玉麒,牛东红,白玉麟,李燕,彭茂潇,蓝天一,卫侃韵,杜蕴超,谢淑媚,何圣耀,阮海灯。一种实验用贝类繁育器。实用新型。专利号ZL201720070595

[4]     牛东红,杜蕴超,李家乐,谢淑媚。一种方便双壳贝类暂养换水和代谢废物排放的暂养箱。实用新型。专利号ZL 201720022932.5

[5]     李家乐,彭茂潇,牛东红,杜蕴超,卫侃韵,王飞,王泽。一种提取双壳贝类血淋巴的操作装置。实用新型。专利号:ZL 201620009773.0

[6]     李家乐,彭茂潇,牛东红,谢淑媚,王泽,王飞,卫侃韵。一种贝类体态快速批量数据测量仪。实用新型。专利号:ZL 201520378894.8

[7]     李家乐,彭茂潇,牛东红,谢淑媚,王飞,王泽,杜蕴超,黄文吉。一种实验用移液枪枪头快速摆放器. 实用新型。专利号:ZL 201520378241.X

[8]     牛东红, 李家乐, 沈和定,王劦,谢淑媚,李多,郑培,王飞,曾仕梅。一种缢蛏家系的建立和良种选育的方法。发明专利。专利号:ZL201310503970.9

[9]     李家乐,王劦,牛东红,赵弘刚,谢淑媚,金凯。一种用于缢蛏的育苗桶。实用新型。专利号:ZL2012207239325.5

[10]刘达博, 李家乐, 牛东红, 冯冰冰。一种贝类育苗简易报警装置。实用新型。专利号2010206952157.0 

 获奖情况

[1]     2019.12  汉宝奖学金优秀青年教师奖

[2]     2019.12  校级教学成果特等奖(排4

[3]     2019.6   遗传学“好课堂”

[4]     2017.6   遗传学“好课堂”

[5]     2014.12  上海海洋大学微课教学比赛 二等奖

[6]     2014.6   上海市青年教师教学竞赛  校级优秀奖

[7]     2013.10  首届全国微课教学比赛上海市三等奖

 联系方式

地址:沪城环路999号水产与生命学院

电话:021-61900438

E-maildhniu@shou.edu.cn